Casandra
Casandra Test Code AL49352Version 1 (DRAFT)
Performing Lab
Lab AllelicaLab Test ID N/A
AbsoluteDx Comprehensive
Clinical Use
Order TestUse
AbsoluteDx Comprehensive analyzes genes associated with hereditary cancer syndromes, cardiovascular risk, metabolic and inherited disorders, neurological and other genetic conditions. Integrates with applicable PRS for comprehensive risk assessment.
Special Instructions
Can be ordered securely through Allelica's platform using saliva samples. Provides broad analysis integrating multiple genetic factors.
Limitations
Limitations depend on the extent of gene coverage for monogenic mutations, robustness of polygenic risk calculations, and cohort data used for ancestry-specific analyses.
Test Details
Methodology
NGS (WGS)
Biomarkers
Utilizes whole-exome and genome sequencing with PRS to deliver comprehensive genetic risk evaluations.
Mutation (96 genes)
BRCA1BRCA2ATMBARD1CDH1CHEK2NF1PALB2PTENRAD51CRAD51DSTK11TP53APCRETBRCA1BRCA2PALB2SDHDSDHAF2SDHCSDHBMAXTMEM127BMPR1ASMAD4TP53MLH1MSH2MSH6PMS2MEN1MUTYHNF2STK11PTENRB1TSC1TSC2VHLWT1FBN1TGFBR1TGFBR2SMAD3ACTA2MYH11BTDGLAOTCGAAATP7BHFEACVRL1ENGRYR1CACNA1SHNF1ARPE65TTRPKP2DSPDSC2TMEM43DSG2RYR2CASQ2TRDNBAG3DESRBM20TNNC1TNNT2LMNAFLNCTTNCALM1CALM2CALM3COL3A1LDLRAPOBPCSK9LDLRAP1MYH7MYBPC3TNNI3TPM1MYL3ACTC1PRKAG2MYL2PLNKCNQ1KCNH2SCN5A
Result Turnaround Time
3-4 weeks
Related Documents
For more information, please review the documents below
Specimen Requirements
Specimen
Saliva
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Leverages non-invasive saliva collection for DNA analysis.