Acute Myeloid Leukemia Mutation Panel by Next Generation Sequencing

Use

This test is used to assess for single gene mutations, including substitutions and smaller insertions and deletions, that may have prognostic and/or therapeutic significance in acute myeloid leukemia (AML). AML is a genetically heterogeneous hematologic malignancy characterized by the clonal expansion of myeloid blasts in the peripheral blood, bone marrow, and/or other tissues, leading to impaired hematopoiesis and bone marrow failure. The panel provides a more cost-effective approach compared to multiple single gene tests and complements the morphologic and cytogenetic workup of myeloid malignancies.