Adenosine Deaminase in CSF
Also known as: ADACSF
Use
The Adenosine Deaminase in CSF test is used to evaluate tuberculous meningitis. This test is particularly useful in the context of diagnosing tuberculous meningitis, which is a serious infection of the membranes covering the brain and spinal cord that requires prompt diagnosis and treatment. Adenosine deaminase is an enzyme involved in the metabolism of purine bases and its elevation in cerebrospinal fluid is associated with mycobacterial infections, including tuberculous meningitis.
Special Instructions
Collect cerebrospinal fluid in a leak-proof container. Ensure specimen remains frozen during transportation to the lab. Indicate the source of the specimen on the requisition form. Be sure the specimen is processed appropriately to avoid preanalytical errors.
Limitations
This test has not been cleared or approved by the US Food and Drug Administration. It is a laboratory-developed test performed in a CLIA certified laboratory intended for clinical purposes. Results should be interpreted in conjunction with clinical findings and other diagnostic procedures. Turbid specimens, whole blood, and bronchoalveolar lavage samples are not acceptable for this test. Improper handling and delays in freezing the specimen may result in inaccurate results.
New York Approved
Methodology
Automated Analyzer (Other)
Biomarkers
LOINC Codes
- 35703-8
Result Turnaround Time
1-4 days
Related Documents
For more information, please review the documents below
Specimen
Cerebrospinal Fluid
Volume
0.5 mL
Minimum Volume
0.2 mL
Container
ARUP Standard Transport Tube
Patient Preparation
Collect specimens in leak-proof container.
Storage Instructions
Specimen must remain frozen until received in lab.
Causes for Rejection
Whole blood. Bronchoalveolar lavage (BAL) specimens. Turbid specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 24 hours |
| Refrigerated | 1 week |
| Frozen | 1 month |