Adenosine Deaminase in Pericardial Fluid
Also known as: ADAPERCAR
Use
The Adenosine Deaminase in Pericardial Fluid test is utilized to evaluate the presence of tuberculous pericarditis. This condition may cause elevated levels of adenosine deaminase in the pericardial fluid, and measuring these levels can aid in the diagnostic process. The test results can contribute to understanding the disease state and guiding appropriate treatment courses, particularly in regions where tuberculosis is prevalent.
Special Instructions
Indicate the source of the pericardial fluid on the requisition form. Ensure that the specimen is properly collected and handled as per the instructions provided to maintain integrity and accuracy of the analysis.
Limitations
The test has not been cleared or approved by the US Food and Drug Administration, indicating its usage as a Laboratory Developed Test (LDT). Accuracy of the test depends on proper handling and processing of the specimen. It is critically important to avoid using whole blood or bronchoalveolar lavage specimens, as these are unacceptable for this assay. Turbid samples may also result in unreliable results and should be rejected. The quantitative spectrophotometry method employed may have limitations in extremely low or high concentration ranges of adenosine deaminase.
Methodology
Automated Analyzer (Clinical Chemistry)
Biomarkers
LOINC Codes
- 49760-2
Result Turnaround Time
1-4 days
Related Documents
For more information, please review the documents below
Specimen
Other
Volume
0.5 mL
Minimum Volume
0.2 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Centrifuge specimen at room temperature, transfer fluid (supernatant) to transport tube, and freeze.
Storage Instructions
Specimen must remain frozen until received in lab.
Causes for Rejection
Whole blood or Bronchoalveolar Lavage (BAL) specimens, turbid specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 24 hours |
| Refrigerated | 1 week |
| Frozen | 30 days |
