Adenosine Deaminase in Pleural Fluid
Also known as: ADAPLEURA
Use
Adenosine Deaminase (ADA) in pleural fluid is used to evaluate tuberculous pleuritis. Tuberculous pleuritis is a condition where there is inflammation of the pleurae due to Mycobacterium tuberculosis infection. Measuring ADA levels in pleural fluid is commonly employed as a diagnostic tool for the presence of tuberculosis, especially in cases of pleural effusion where differential diagnosis is needed to distinguish between tuberculous and non-tuberculous causes.
Special Instructions
Collect specimens in a leak-proof container and centrifuge at room temperature. After centrifugation, transfer 0.5 mL of the supernatant fluid to an ARUP Standard Transport Tube and freeze. It is essential to indicate the source of the pleural fluid on the requisition form when submitting the samples to the laboratory.
Limitations
This test has been developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration, and thus is classified as a Laboratory Developed Test (LDT). The test must be stored frozen until received by the lab to ensure accurate results. Unacceptable conditions include whole blood, Bronchoalveolar lavage (BAL) specimens, and turbid specimens, which could lead to inaccurate measurements or test rejections.
New York Approved
Methodology
Automated Analyzer (Clinical Chemistry)
Biomarkers
LOINC Codes
- 35704-6
Result Turnaround Time
1-4 days
Related Documents
For more information, please review the documents below
Specimen
Body Fluid
Volume
0.5 mL
Minimum Volume
0.2 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Collect pleural fluid in a leak-proof container. Centrifuge at room temperature and transfer supernatant to a transport tube and freeze.
Storage Instructions
Specimen must remain frozen until received in lab.
Causes for Rejection
Whole blood, Bronchoalveolar lavage (BAL) specimens, turbid specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 24 hours |
| Refrigerated | 1 week |
| Frozen | 1 month |