Antibiotic Level, Nafcillin
Also known as: ML NAF
Use
The test is used for monitoring the levels of the antimicrobial drug, nafcillin, to ensure therapeutic efficacy and avoid toxicity. It is significant for therapeutic drug monitoring in patients receiving nafcillin, taking into account factors like the dose, route of administration, and any underlying patient conditions that may influence drug levels.
Special Instructions
It's important to provide the time of the last dose and a list of all antibiotics that the patient is receiving or has received in the past 48 hours for accurate interpretation. Aseptically collect 2 mL serum and freeze in a sterile tube, avoiding SST or plasma.
Limitations
The bioassay may be interfered with by the presence of other antimicrobial agents. Furthermore, inherent patient differences, such as underlying physical conditions or differences in drug dosage and administration route, may influence nafcillin levels. Trough serum concentrations are not well established, which could affect the assessment of the drug's pharmacokinetics in some clinical scenarios.
New York Approved
Methodology
Other
Biomarkers
LOINC Codes
- 10993-4
Result Turnaround Time
2-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
2 mL
Minimum Volume
1 mL
Container
sterile tube (ARUP supply #43115)
Collection Instructions
Aseptically remove 2 mL serum to a sterile tube and freeze. Avoid SST or plasma.
Causes for Rejection
SST or plasma are unacceptable conditions.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 2 hours |
| Refrigerated | 24 hours |
| Frozen | 1 week |