Antimicrobial Susceptibility - Extended Spectrum Beta Lactamase
Also known as: MA ESBL
Use
This test is used to determine in vitro susceptibility of extended spectrum beta lactamase (ESBL) producing organisms such as E. coli, Klebsiella species, and Proteus mirabilis to antimicrobial agents. This information is crucial for guiding appropriate antimicrobial therapy in patients infected with these organisms.
Special Instructions
An additional processing fee will be charged for organisms not submitted in pure culture. Isolate identification and specimen source are required. If species identification is not provided, it will be performed at ARUP with additional charges.
Limitations
Currently, there are no CLSI guidelines for testing organisms other than E. coli, Klebsiella spp., and Proteus mirabilis for ESBL activity. The CLSI-approved method does not rule out resistance mechanisms other than ESBL production.
New York Approved
Methodology
Culture-based
Biomarkers
LOINC Codes
- 6984-9
Result Turnaround Time
2-4 days
Related Documents
For more information, please review the documents below
Specimen
Other
Volume
Not provided
Minimum Volume
Not provided
Container
Sealed container with pure culture on agar slant or bacterial transport media
Patient Preparation
Collect actively growing E. coli, Klebsiella species, or Proteus mirabilis in pure culture.
Storage Instructions
Transport at room temperature.
Causes for Rejection
Mixed cultures or non-viable organisms
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 1 week |
| Refrigerated | 48 hours |
| Frozen | Unacceptable |