Antiviral Susceptibility, Herpes Simplex Virus, Foscarnet
Also known as: HSVSUS FOS
Use
This test is used to determine the in-vitro susceptibility of cultured herpes simplex virus (HSV) isolates to foscarnet. It is particularly used in clinical scenarios where it is crucial to identify resistant strains of HSV to inform appropriate antiviral treatment strategies. Proper identification of resistance helps in managing and tailoring patient-specific antiviral treatments, especially for those patients who do not respond to standard antiviral therapies.
Special Instructions
If a direct patient specimen is submitted, Herpes Simplex Virus Culture (0065005) will be additionally performed as the test requires an HSV isolate not available from direct specimens. Each specimen must be placed in an individually sealed bag for submission.
Limitations
This test requires HSV isolates that are not obtainable directly from patient samples, meaning the test relies entirely on culture growth. The results may take longer due to the dependency on culture growth rates, and there is no FDA approval for this test, which is only performed for clinical purposes in a CLIA certified laboratory. Furthermore, any isolates that do not reach 3-4+ positivity may incur additional processing fees.
New York Approved
Methodology
Cell-based / Cytometry
Biomarkers
LOINC Codes
- 256-8
- 42317-8
Result Turnaround Time
14-21 days
Related Documents
For more information, please review the documents below
Specimen
Cultured Cells
Volume
Not provided
Minimum Volume
Not provided
Container
Individually sealed bag
Collection Instructions
Isolate from cell culture (3-4+ positivity).
Causes for Rejection
Isolate fails to grow to 3-4+ positivity
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 72 hours |
| Frozen | 1 month |