Apolipoprotein B/A Ratio

Also known as: APO B/A

Clinical Use

Use

The Apolipoprotein B/A Ratio test is used as a secondary cardiovascular risk screen for specific populations. It provides an estimate of the risk for major adverse cardiovascular events in adults by measuring the ratio of apolipoprotein B to apolipoprotein A. This ratio is useful in evaluating cardiovascular health and risk, particularly when traditional lipid panel assessments may not be sufficient to assess a patient's risk profile.

Special Instructions

Not provided.

Limitations

The Apolipoprotein B/A Ratio test, being reliant on serum or plasma measurements, may be affected by factors that influence these protein levels. Additionally, patient compliance with fasting requirements is crucial for accurate measurement. The test does not replace comprehensive lipid profiling but serves as an adjunct in specific risk assessment scenarios. Interpretation of the results should consider potential biological variability and the clinical context of the patient.

Test Details

New York Approved

Methodology

Immunoassay

Biomarkers

Apolipoprotein A-1

Analyte

Apolipoprotein A-1

Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)

Apolipoprotein B

Analyte

Apolipoprotein B

Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)

LOINC Codes

Order Codes

1874-7 - Apo B/Apo A-I SerPl

Result Codes

1871-3 - Apo B100 SerPl-mCnc
1869-7 - Apo A-I SerPl-mCnc

Result Turnaround Time

1 day

Specimen

Serum

Volume

1 mL

Minimum Volume

0.5 mL

Container

ARUP standard transport tube

Collection Instructions

Collect using a serum separator tube. Allow specimen to clot completely at room temperature. Separate serum from cells ASAP or within 2 hours of collection.