ATRX by Immunohistochemistry
Also known as: ATRX IHC
Use
This test is used to detect ATRX protein expression in tissue samples, helping in the classification and understanding of various tumors, notably in brain tumors. ATRX mutations or deletions are associated with certain cancers and can give insights into the tumor's behavior and potential treatment strategies.
Special Instructions
Not provided.
Limitations
The test's performance characteristics have been determined by ARUP Laboratories, but it has not been cleared or approved by the US Food and Drug Administration. Results should be interpreted in the context of clinical and other diagnostic findings.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
ATRX
Protein
LOINC Codes
- 53841-3 - ATRX gene Mut Anl Bld/T
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
2 slides
Container
Tissue block or slides in a tissue transport kit
Collection Instructions
Formalin fix (10 percent neutral buffered formalin) and paraffin embed specimen. Do not oven bake if sending precut slides.
Storage Instructions
Room temperature is preferred; refrigerate if necessary. Ship in a cooled container during summer months.
Causes for Rejection
Specimens with non-representative tissue type or depleted specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinitely |
| Refrigerated | Indefinitely |
| Frozen | Unacceptable |
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