Autism and Intellectual Disability Comprehensive Panel
Also known as: AID COMP
Use
The Autism and Intellectual Disability Comprehensive Panel is designed for comprehensive genetic evaluation of individuals with autism spectrum disorder (ASD) and/or intellectual disability (ID). The test includes a series of genetic assessments to identify potential genetic syndromes or metabolic disorders associated with these conditions. It aids clinicians in determining a genetic basis by evaluating patient's genomic variations and relevant biochemical markers linked to ASD and ID.
Special Instructions
Not provided.
Limitations
This test has not been cleared or approved by the US Food and Drug Administration, though it is performed in a CLIA-certified laboratory with established performance characteristics by ARUP Laboratories. Limitations include potential diagnostic errors due to rare sequence variations and possible undetectable rare FMR1 variants. Copy number variants below the platform resolution, sequence-level mutations, and low-level mosaicism may not be detected. Results may not provide specific structural information related to genomic imbalance, necessitating additional cytogenetic testing by chromosome analysis or FISH as warranted.
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 39001-3 - 3OH-Isovalerylcarn SerPl-sCnc
- 30191-1 - Acetylcarn SerPl-sCnc
- 30551-6 - Propionylcarn SerPl-sCnc
- 51413-3 - Butyryl+Isobutyrylcarn SerPl-sCnc
- 30531-8 - Isovaleryl+MeButyrylcarn SerPl-sCnc
- 30349-5 - Glutarylcarn SerPl-sCnc
- 30358-6 - Hexanoylcarn SerPl-sCnc
- 30540-9 - Octanoylcarn SerPl-sCnc
- 30541-7 - Octenoylcarn SerPl-sCnc
- 30327-1 - Decanoylcarn SerPl-sCnc
- 30328-9 - Decenoylcarn SerPl-sCnc
- 30331-3 - Dodecanoylcarn SerPl-sCnc
- 30332-1 - Dodecenoylcarn SerPl-sCnc
- 30233-1 - 3OH-Dodecanoylcarn SerPl-sCnc
- 30565-6 - Tdecanoylcarn SerPl-sCnc
- 30566-4 - Tdecenoylcarn SerPl-sCnc
- 30564-9 - Tdecadienoylcarn SerPl-sCnc
- 30238-0 - 3OH-Tdecanoylcarn SerPl-sCnc
- 30190-3 - 3OH-Tdecenoylcarn SerPl-sCnc
- 30356-0 - Palmitoylcarn SerPl-sCnc
- 30357-8 - Palmitoleylcarn SerPl-sCnc
- 30234-9 - 3OH-Palmitoylcarn SerPl-sCnc
- 30235-6 - 3OH-Palmitoleylcarn SerPl-sCnc
- 30560-7 - Stearoylcarn SerPl-sCnc
- 30542-5 - Oleoylcarn SerPl-sCnc
- 30534-2 - Linoleoylcarn SerPl-sCnc
- 35656-8 - 3OH-stearoylcarn SerPl-sCnc
- 30312-3 - 3OH-Oleoylcarn SerPl-sCnc
- 30237-2 - 3OH-Linoleoylcarn SerPl-sCnc
- 45321-7 - FMR1 allele1 CGG Rpt EntNum Bld/T
- 45322-5 - FMR1 allele 2 CGG Rpt EntNum Bld/T
- 41107-4 - FMR1 gene Mut Anl Bld/T
- 36913-2 - FMR1 gene Mut Anl Bld/T
- 20636-7 - Alanine SerPl-sCnc
- 20637-5 - Arginine SerPl-sCnc
- 20639-1 - Aspartate SerPl-sCnc
- 20640-9 - Citrulline SerPl-sCnc
- 20643-3 - Glutamine SerPl-sCnc
- 20642-5 - Glutamate SerPl-sCnc
- 20644-1 - Glycine SerPl-sCnc
- 20645-8 - Histidine SerPl-sCnc
- 20647-4 - OH-Proline SerPl-sCnc
- 20648-2 - Isoleucine SerPl-sCnc
- 20649-0 - Leucine SerPl-sCnc
- 20650-8 - Lysine SerPl-sCnc
- 20651-6 - Methionine SerPl-sCnc
- 20652-4 - Ornithine SerPl-sCnc
- 14875-9 - Phe SerPl-sCnc
- 20655-7 - Proline SerPl-sCnc
- 20656-5 - Serine SerPl-sCnc
- 20657-3 - Taurine SerPl-sCnc
- 20658-1 - Threonine SerPl-sCnc
- 20660-7 - Tyrosine SerPl-sCnc
- 20661-5 - Valine SerPl-sCnc
- 20646-6 - (Hcys)2 SerPl-sCnc
- 22670-4 - Alloisoleucine SerPl-sCnc
- 25112-4 - Lactate/Creat Ur-sRto
- 25132-2 - Pyruvate/Creat Ur-sRto
- 25136-3 - Succinate/Creat Ur-sRto
- 29507-1 - A-Ketoglut/Creat Ur-sRto
- 25101-7 - Fumarate/Creat Ur-sRto
- 25116-5 - Methylmalonate/Creat Ur-sRto
- 29509-7 - B-OH-Butyr/Creat Ur-sRto
- 29524-6 - Acetoacet/Creat Ur-sRto
- 25083-7 - 2Oxo3Me-valerate/Creat Ur-sRto
- 25084-5 - 2Oxoisocaproate/Creat Ur-sRto
- 25085-2 - 2Oxoisovalerate/Creat Ur-sRto
- 25099-3 - Ethylmalonate/Creat Ur-sRto
- 29859-6 - Adipate/Creat Ur-sRto
- 25135-5 - Suberate/Creat Ur-sRto
- 25134-8 - Sebacate/Creat Ur-sRto
- 25088-6 - 4OH-phenylacetate/Creat Ur-sRto
- 25089-4 - 4OH-phenyllactate/Creat Ur-sRto
- 29519-6 - 4OH-phenylpyruvate/Creat Ur-sRto
- 25137-1 - Succinylacetone/Creat Ur-sRto
- 46132-7 - GAG/Creat Ur-Rto
- 22672-0 - Cystine SerPl-sCnc
- 33244-5 - Guanidinoacetate SerPl-sCnc
- 15045-8 - Creatine SerPl-sCnc
- 14683-7 - Creat Ur-sCnc
- 34155-2 - Guanidinoacetate/Creat Ur-sRto
- 34275-8 - Creatine/Creat Ur-sRto
- 62375-1 - Microarray platform
- 11526-1 - Pathology study
- 20634-2 - A-Aminobutyr SerPl-sCnc
- 26600-7 - AAA SerPl-sCnc
- 32227-1 - Argininosuccinate SerPl-sCnc
- 26605-6 - B-AIB SerPl-sCnc
- 26604-9 - B-Alanine SerPl-sCnc
- 26608-0 - Ethanolamine SerPl-sCnc
- 26609-8 - GABA SerPl-sCnc
- 26613-0 - Sarcosine SerPl-sCnc
- 20659-9 - Tryptophan SerPl-sCnc
- 26599-1 - Anserine SerPl-sCnc
- 20638-3 - Asparagine SerPl-sCnc
- 26607-2 - Cystathionin SerPl-sCnc
- 55876-7 - Homocitrulline SerPl-sCnc
- 26610-6 - OH-Lysine SerPl-sCnc
Result Turnaround Time
5-18 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
15 mL
Minimum Volume
10 mL
Container
ARUP Standard Tubes
Collection Instructions
Random urine collection. Avoid dilute urine when possible.
Patient Preparation
Morning void preferred.
Storage Instructions
Critical frozen; must be submitted separately when multiple tests are ordered.
Causes for Rejection
Specimens exposed to more than one freeze/thaw cycle. Specimens containing preservatives.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Unacceptable |
| Refrigerated | Unacceptable |
| Frozen | 1 month |
Other tests from different labs that may be relevant