Autoimmune Epilepsy Panel, Serum
Also known as: AIEPS
Use
The Autoimmune Epilepsy Panel, Serum is utilized to evaluate new acute-to subacute-onset epilepsy and incomplete seizure control within less than 2 years. This panel is particularly recommended for patients displaying new-onset movement disorders or if there are subacute-onset neurologic symptoms without seizures. It allows for the detection of specific antibodies that are associated with autoimmune neurologic diseases, aiding in the differential diagnosis and management of autoimmune-mediated epilepsy and related neurological disorders.
Special Instructions
Not provided.
Limitations
This test does not provide a definitive diagnostic result on its own and should be interpreted in conjunction with the patient's clinical history and other laboratory findings. False-negative results may occur, and negative results do not preclude the presence of autoimmune neurological conditions. Also, the presence of these antibodies can be associated with various tumor types, detailed evaluation for the underlying neoplasm is recommended in such cases.
New York Approved
Methodology
Cell-based / Cytometry (Flow Cytometry)
Biomarkers
LOINC Codes
- 94385-2 - Amphiphysin IgG Ser Ql Line blot
- 56540-8 - GAD65 Ab Ser IA-aCnc
- 80221-5 - NMDAR IgG Titr Ser IF
- 61177-2 - Paraneoplastic Ab Ser Ql IF
- 82979-6 - CASPR2 IgG SerPl Ql IF
- 82978-8 - LGI1 IgG SerPl Ql IF
- 72504-4 - CV2 Ab SerPl Ql IF
- 82733-7 - AMPAR 1+2 IgG SerPl Ql IF
- 93428-1 - GABABR IgG SerPl Ql CBA IFA
- 82444-1 - Glial nuc type 1 Ab Ser Ql Line blot
- 94676-4 - DPPX IgG Ser Ql CBA IFA
- 101874-6 - GABAAR IgG Ser Ql CBA IFA
- 93498-4 - mGluR1 IgG Ser Ql CBA IFA
- 82423-5 - Ma+Ta Ab Ser Ql Line blot
Result Turnaround Time
3-10 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
Not provided
Minimum Volume
0.5 mL/aliquot
Container
ARUP standard transport tubes
Collection Instructions
Separate from cells ASAP or within 2 hours of collection. Transfer three 1 mL serum aliquots.
Causes for Rejection
Amniotic fluid, ocular fluid, peritoneal fluid, synovial fluid, CSF, or plasma. Contaminated, hemolyzed, icteric, or lipemic specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 24 hours |
| Refrigerated | 1 week |
| Frozen | 1 month |
Other tests from different labs that may be relevant