Bilirubin, Direct and Total, Serum or Plasma

Also known as: BILI

Clinical Use

Use

This test is used to measure the levels of bilirubin, a yellow compound found in bile, in the blood. Bilirubin testing is significant for evaluating liver function, diagnosing jaundice, and managing conditions like primary biliary cholangitis and autoimmune hepatitis. It helps in differentiating between disorders causing red blood cell breakdown and those causing impaired liver processing of bilirubin. The test may aid in diagnosing underlying health issues affecting the liver and bile duct systems.

Special Instructions

Not provided.

Limitations

Certain conditions, medications, or improper sample handling can alter bilirubin levels, leading to potential inaccuracies. Bilirubin levels can be affected by hemolysis, lipemia, and exposure to light. Testing does not differentiate the specific cause of liver dysfunction or distinguish between different forms of jaundice in all cases.

Test Details

New York Approved

Methodology

Other

Biomarkers

Bilirubin Direct

Analyte

Bilirubin Direct

Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)

Bilirubin, Total

Analyte

Bilirubin, Total

Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)

LOINC Codes

Order Codes

1975-2 - Bilirub SerPl-mCnc

Result Codes

1968-7 - Bilirub Direct SerPl-mCnc

Result Turnaround Time

1 day

Specimen

Plasma

Volume

1 mL

Minimum Volume

0.2 mL

Container

ARUP amber transport tube

Collection Instructions

Collect using a plasma separator tube or serum separator tube. Protect from light. Allow serum tube to clot completely at room temperature. Separate serum or plasma from cells within 2 hours of collection.