Blastomyces dermatitidis Antibodies by Immunoassay with Reflex to Immunodiffusion, CSF

Casandra

Casandra Test Code AR89058Version 1 (DRAFT)

Performing Lab

Lab ARUP LaboratoriesLab Test ID 3000231CPT Code 86612

Blastomyces dermatitidis Antibodies by Immunoassay with Reflex to Immunodiffusion, CSF

Also known as: BLST R CSF

Clinical Use

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Use

This test is used to detect antibodies against Blastomyces dermatitidis in cerebrospinal fluid (CSF). It is intended for the diagnosis of blastomycosis, a fungal infection caused by Blastomyces species. Detection of antibodies in CSF can aid in diagnosing central nervous system involvement in blastomycosis. It is recommended to consider this test in conjunction with histology or culture for a comprehensive diagnostic approach.

Special Instructions

If antibodies are equivocal or positive by immunoassay, the test reflexes to immunodiffusion. Additional charges apply for the reflex test. Prior to specimen collection, approval from the New York Department of Health is required as the test is not NY state approved. A Non-Permitted Laboratory Request Form must be submitted and approved.

Limitations

The test detects total antibodies against yeast-phase antigens from Blastomyces dermatitidis. An elevated EIA result combined with a negative immunodiffusion result may indicate an early infection or a falsely elevated EIA result, suggesting the need for repeat testing. It is important to note that a negative immunodiffusion result does not exclude the possibility of infection.

Test Details