Bone Specific Alkaline Phosphatase
Also known as: BSAP
Use
The Bone Specific Alkaline Phosphatase (BSAP) test is used to evaluate bone formation activity. It is an important marker for diagnosing and monitoring conditions associated with increased or decreased bone turnover, such as osteoporosis. The test helps in assessing bone metabolic diseases, monitoring treatment response, and in the differential diagnosis of skeletal disorders.
Special Instructions
The test requires serum separator tube or green (sodium or lithium heparin) tube for specimen collection. Proper handling and storage are crucial to avoid specimen degradation. Transfer serum or plasma to an ARUP Standard Transport Tube and keep it frozen. Patients should follow any specific preparation instructions provided prior to collection to ensure accurate results.
Limitations
This test may be influenced by the presence of liver alkaline phosphatase, potentially affecting its accuracy. Approximately 2.5 to 5.8 µg/L of bone specific alkaline phosphatase can be added to the result for each 100 U/L of liver alkaline phosphatase. Care must be taken when interpreting results in patients with elevated liver alkaline phosphatase levels.
New York Approved
Methodology
Immunoassay
Biomarkers
LOINC Codes
- 17838-4
Result Turnaround Time
1 day
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL
Minimum Volume
0.3 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Collect in serum separator tube or green (sodium or lithium heparin) tube. Transfer serum or plasma to ARUP Standard Transport Tube.
Storage Instructions
Store frozen. Separate specimens must be submitted when multiple tests are ordered.
Causes for Rejection
Urine. Grossly hemolyzed specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 2 hours |
| Refrigerated | 48 hours |
| Frozen | 2 months |