Calprotectin, Fecal by Immunoassay
Also known as: CALPRO FEC
Use
The fecal calprotectin test aids in the differentiation of inflammatory bowel disease (IBD) from irritable bowel syndrome (IBS) and other functional gastrointestinal disorders. It is also useful for monitoring IBD and predicting potential relapses. The presence of calprotectin in feces is an indicator of neutrophil presence, but is not exclusively specific to IBD, as other conditions like gastrointestinal infections or colorectal cancer might also cause elevated levels.
Special Instructions
Transfer 5 g of stool to an unpreserved stool transport vial (ARUP Supply #40910). The transport vial is available through eSupply using ARUP Connect(TM) or by contacting ARUP Client Services. The minimum required quantity is 1 g.
Limitations
Fecal calprotectin levels are not specific solely for IBD; elevated levels can be seen in other intestinal conditions such as infections and colorectal cancer. A positive calprotectin result alone is insufficient to diagnose IBD. Levels may fluctuate as patients transition between active and inactive disease stages.
Methodology
Immunoassay (CLIA)
Biomarkers
LOINC Codes
- 38445-3
Result Turnaround Time
1-4 days
Related Documents
For more information, please review the documents below
Specimen
Stool
Volume
5 g
Minimum Volume
1 g
Container
unpreserved stool transport vial
Collection Instructions
Transfer 5 g stool to an unpreserved stool transport vial.
Causes for Rejection
Specimens in media or preservatives.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Unacceptable |
| Refrigerated | 7 days |
| Frozen | 30 days |
