Candida albicans Antibodies IgA, IgG, and IgM by ELISA
Also known as: CANDIDA AB
Use
This test is used to detect antibodies to Candida albicans, including IgA, IgG, and IgM, using a semi-quantitative enzyme-linked immunosorbent assay (ELISA) method. It is intended to help diagnose Candida infections by observing changes in antibody levels over time. A significant change in antibody levels between two samples collected at different times is considered the best evidence for a current infection. Persistent low levels of IgM antibodies may occasionally be found more than 12 months post-infection, indicating past exposure.
Special Instructions
Not provided.
Limitations
This test is limited in its clinical utility as it does not provide conclusive evidence of a current Candida infection in isolation. It is most effective when used to observe changes over time in antibody levels. The results can be influenced by past infections as low levels of IgM antibodies may persist for over 12 months. Furthermore, results can be affected by bacterially contaminated, heat-inactivated, hemolyzed, icteric, lipemic, or turbid specimens, which are considered unacceptable conditions for testing.
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 7172-0 - C albicans IgG Qn
- 56150-6 - C albicans IgM Ser-aCnc
- 56151-4 - C albicans IgA Ser-aCnc
Result Turnaround Time
1-8 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL
Minimum Volume
0.15 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Separate serum from cells ASAP or within 2 hours of collection.
Causes for Rejection
Bacterially contaminated, heat-inactivated, hemolyzed, icteric, lipemic, or turbid specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 6 months |
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