CD123 by Immunohistochemistry
Also known as: CD123 IHC
Use
The CD123 by Immunohistochemistry test aids in the evaluation of tissue samples for the presence of CD123, which is the alpha subunit of the interleukin-3 receptor. It is commonly used in the diagnostic workup of hematological malignancies, including certain types of leukemia and lymphoma where CD123 is overexpressed. This test can help in differentiating between subtypes of malignancies based on CD123 expression.
Special Instructions
IMMUNOHISTOCHEMISTRY ORDERING AND SUBMISSION DETAILS: Submit electronic request. If you do not have electronic ordering capability, use an ARUP Immunohistochemistry Stain Form (#32978) with an ARUP client number. Protect paraffin block and/or slides from excessive heat during transport. For additional technical details, contact ARUP Client Services at (800) 522-2787.
Limitations
This test is performed as a stain and return (technical) service only and may not provide comprehensive diagnostic information if used alone. Results should be interpreted in conjunction with other clinical findings and laboratory tests. As a laboratory-developed test, it has not been cleared or approved by the US Food and Drug Administration.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
LOINC Codes
- 94736-6
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
2 slides
Container
tissue transport kit (ARUP supply #47808)
Collection Instructions
Formalin fix (10 percent neutral buffered formalin) and paraffin embed specimen (cells must be prepared into a cellblock). Transport tissue block or 5 unstained (3- to 5-micron thick sections), positively charged slides.
Storage Instructions
Protect paraffin block and/or slides from excessive heat.
Causes for Rejection
Depleted specimens. Specimens submitted with non-representative tissue type.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinitely |
| Refrigerated | Indefinitely |
| Frozen | Indefinitely |