CD1a by Immunohistochemistry
Also known as: CD1A IHC
Use
The CD1a by Immunohistochemistry test is used to detect the presence of the CD1a protein on tissue or cells. CD1a is commonly used in the diagnosis of certain histiocytic disorders, such as Langerhans cell histiocytosis. It is a valuable tool in the immunophenotypic characterization of histiocytes, helping to distinguish between different types of histiocytic proliferations.
Special Instructions
Submit electronic request for the test. If electronic ordering is not available, use an ARUP Immunohistochemistry Stain Form (#32978) with an ARUP client number. For additional technical details, contact ARUP Client Services.
Limitations
This test is performed as a stain and return (technical) service only. It has not been cleared or approved by the US Food and Drug Administration. The performance characteristics of the test were determined by ARUP Laboratories and conducted in a CLIA certified laboratory. The test is intended solely for clinical purposes and should not be used as the sole basis for diagnosis or patient management.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
LOINC Codes
- 94736-6
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
2 unstained slides
Container
Tissue transport kit (ARUP supply #47808)
Collection Instructions
Formalin fix (10 percent neutral buffered formalin) and paraffin embed specimen (cells must be prepared into a cellblock). Protect paraffin block and/or slides from excessive heat. Transport tissue block or 5 unstained (3- to 5-micron thick sections), positively charged slides in a tissue transport kit.
Storage Instructions
Room temperature or refrigerated. Ship in cooled container during summer months.
Causes for Rejection
Depleted specimens. Specimens submitted with non-representative tissue type.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinitely |
| Refrigerated | Indefinitely |
| Frozen | Unacceptable |