CD200 by Immunohistochemistry
Also known as: CD200 IHC
Use
This test is used for the detection of CD200 protein expression in tissues. CD200, also known as OX-2, is a type I membrane glycoprotein that is involved in the regulation of immune responses. Immunohistochemistry for CD200 is employed in clinical settings to assist in the differential diagnosis of hematologic neoplasms.
Special Instructions
Prepare and fix tissue specimens in 10 percent neutral buffered formalin and embed in paraffin. Protect from heat and transport in a tissue transport kit. ARUP offers these kits for supply. Do not oven bake precut slides.
Limitations
The performance characteristics of this test were determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration, which may affect regulatory acceptance in certain jurisdictions. The test is performed as a technical stain and return service, and interpretive limitations may apply based on specific tissue quality and preservation.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
LOINC Codes
- 94736-6
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
2 slides
Container
Tissue transport kit (ARUP supply #47808)
Collection Instructions
Formalin fix (10 percent neutral buffered formalin) and paraffin embed specimen. Transport tissue block or 5 unstained (3- to 5-micron thick sections), positively charged slides.
Storage Instructions
Protect paraffin block and/or slides from excessive heat.
Causes for Rejection
Specimens submitted with non-representative tissue type. Depleted specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinitely |
| Refrigerated | Indefinitely |
| Frozen | Unacceptable |