CD22 by Immunohistochemistry

Casandra

Casandra Test Code AR59197Version 1 (DRAFT)

Performing Lab

Lab ARUP LaboratoriesLab Test ID 3004795CPT Code 88342

CD22 by Immunohistochemistry

Also known as: CD22IHC

Clinical Use

Order Test

Use

The CD22 by Immunohistochemistry test is used for the detection of CD22 protein expression in tissues. It is primarily utilized in the diagnostic evaluation of B-cell related malignancies, such as various types of lymphoma. CD22 is a surface antigen found on mature B-cells and is useful in distinguishing B-cell lymphomas from other types of lymphoid or non-lymphoid malignancies. The test aids pathologists and oncologists in the identification and classification of hematologic neoplasms based on the immunophenotypic profile.

Special Instructions

Not provided.

Limitations

This test is limited by the quality and representativeness of the submitted tissue sample. Nonrepresentative tissue or depleted specimens are unacceptable. Interpretive results rely on the quality of the staining and the experience of the interpreting pathologist. It is crucial that slides are neither overly dried nor improperly fixed, as these conditions can lead to suboptimal staining and potentially erroneous interpretation. Furthermore, as a laboratory developed test, it is not FDA-approved, although it is New York State approved.

Test Details

New York Approved

Methodology

Immunoassay (IHC)

Biomarkers

CD22

Protein

IHC

Expression • Ordinal Score (e.g., TPS, CPS, H-score)

Result Turnaround Time

1-3 days

Specimen

Tissue (FFPE)

Volume

Not provided

Minimum Volume

Not provided

Container

Tissue Transport Kit (ARUP supply #47808)

Collection Instructions

Collect tissue or cells. Formalin fix (10 percent neutral buffered formalin) and paraffin embed specimen. Protect paraffin block and/or slides from excessive heat.