Ceruloplasmin
Also known as: CERU
Use
The Ceruloplasmin test is used as an initial screening test for Wilson disease or other copper transport disorders. It measures the level of ceruloplasmin in the blood, which is a protein that binds copper and helps to carry it in the blood. Abnormal levels of ceruloplasmin can indicate a variety of conditions, including Wilson disease, liver disease, and diseases of copper metabolism.
Special Instructions
Fasting specimen preferred. It's important to separate the serum or plasma from cells as soon as possible, ideally within 2 hours of collection.
Limitations
The test cannot be performed on EDTA plasma or hemolyzed specimens, as these conditions can affect the accuracy of the results. Additionally, there may be variability in ceruloplasmin levels due to factors such as age, gender, and overall health, which can affect the interpretation of results.
New York Approved
Methodology
Immunoassay (Quantitative Immunoturbidimetry)
Biomarkers
LOINC Codes
- 2064-4
Result Turnaround Time
1 day
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Collect using Serum Separator Tube (SST) or Plasma collected in Green (Lithium Heparin). Allow specimen to clot completely at room temperature. Separate from cells ASAP or within 2 hours of collection and transfer specified volume.
Patient Preparation
Fasting specimen preferred.
Causes for Rejection
EDTA plasma or hemolyzed specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 8 days |
| Refrigerated | 2 weeks |
| Frozen | 1 year |