Chikungunya Antibody, IgM
Also known as: CHIKM
Use
This test is used to aid in the diagnosis of chikungunya viral infection during the acute phase of the disease, which typically occurs more than five days after the onset of symptoms. It may also be considered for differential diagnosis with other arthropod-borne viruses that present similar symptoms, especially when considered alongside clinical presentation and travel history.
Special Instructions
Parallel testing is preferred, and convalescent specimens must be received within 30 days from the receipt of the acute specimens. Specimens should be plainly marked as 'acute' or 'convalescent' to ensure proper differentiation during analysis.
Limitations
The test may not detect chikungunya IgM antibodies at levels below the assay's detection limit. Equivocal results can occur, which may necessitate repeat testing in 10-14 days. Results may be impacted by factors such as specimen contamination, hemolysis, or the presence of interfering substances like lipemic or heat-inactivated samples.
New York Approved
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 83067-9
Result Turnaround Time
1-8 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.15 mL
Container
ARUP standard transport tube
Collection Instructions
Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP standard transport tube.
Storage Instructions
Refrigerated.
Causes for Rejection
Contaminated, heat-inactivated, hemolyzed, or severely lipemic specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 year |