Chromium, Serum
Also known as: CR S
Use
This test is useful in assessing chromium deficiency or overload. Elevated serum chromium levels can be associated with metal-on-metal total hip replacement implants. Chromium levels should be interpreted in the context of the overall clinical scenario, especially in patients with metal-on-metal prosthetics. For the assessment of hexavalent chromium exposure, Chromium, RBC (2014505) is preferred.
Special Instructions
Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, and nonessential over-the-counter medications, upon the advice of their physician, to avoid potential interference with test results.
Limitations
Elevated serum chromium levels may occur due to contamination from skin or collection-related issues, such as the use of noncertified metal-free collection containers. High serum chromium levels may also occur in asymptomatic patients with metal-on-metal prosthetics and should be carefully evaluated.
New York Approved
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 5622-6
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
2 mL
Minimum Volume
0.5 mL
Container
ARUP Trace Element-Free Transport Tube
Collection Instructions
Royal blue (no additive). Separate from cells ASAP or within 2 hours of collection. Transfer serum to ARUP Trace Element-Free Transport Tube without using utensils (e.g., syringes, needles).
Patient Preparation
Discontinue nutritional supplements, vitamins, minerals, and nonessential medications upon physician's advice.
Storage Instructions
Room temperature. Also acceptable: Refrigerated or frozen.
Causes for Rejection
Plasma. Royal blue (EDTA) or separator tubes. Specimens not separated from clot within 2 hours. Specimens in incorrect tubes.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinitely |
| Refrigerated | Indefinitely |
| Frozen | Indefinitely |