Chromium, Urine
Also known as: CR-U
Use
Urine chromium concentrations can be used to monitor short-term chromium exposure. Hexavalent chromium, which is highly toxic, influences the distribution and can lead to various symptoms such as dermatitis, impairment of pulmonary function, gastroenteritis, hepatic necrosis, bleeding, and acute tubular necrosis. Chromium levels in urine help in assessing these exposures effectively.
Special Instructions
Patients should discontinue nutritional supplements, vitamins, minerals, and non-essential over-the-counter medications based on physician advice. It's also crucial to avoid urine collection for a minimum of 72 hours post-exposure to iodinated or gadolinium-based contrast media, and a minimum of 14 days for patients with impaired kidney function post-contrast media exposure.
Limitations
Elevated results may arise from contamination due to non-trace element-free collection containers. Confirmation with a second specimen collected in a certified trace element-free container is recommended if contamination is suspected. Results can be influenced by excessive skin or collection-related contamination.
New York Approved
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 35674-1
- 2162-6
- 5624-2
- 29919-8
- 19153-6
- 30211-7
- 21201-9
- 35674-1
- 2162-6
- 5624-2
- 29919-8
- 19153-6
- 30211-7
- 21201-9
Result Turnaround Time
1-5 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
8 mL
Minimum Volume
1 mL
Container
ARUP Trace Element-Free Transport Tubes (#43116)
Collection Instructions
Collect 24-hour or random urine collection in a plastic container. Refrigeration during and after collection is adequate if tested within 14 days.
Patient Preparation
Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, and non-essential over-the-counter medications. Collections from patients receiving contrast media should be delayed accordingly.
Storage Instructions
Store refrigerated. Also acceptable at room temperature or frozen.
Causes for Rejection
Urine collected within 72 hours after contrast media; acid-preserved urine; specimens contaminated with blood or fecal material; non-trace element-free transport tubes (except original device).
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 1 week |
| Refrigerated | 2 weeks |
| Frozen | 1 year |