Chromogenic Factor VIII, Activity
Also known as: CHROM F8
Use
This test is useful in combination with Factor VIII, Activity (0030095) for the initial diagnosis of mild hemophilia A. It is also used to measure factor VIII activity in the presence of a lupus anticoagulant. The test is helpful in monitoring certain extended half-life factor VIII replacement products and in measuring native factor VIII or factor VIII concentrates in patients on emicizumab (Hemlibra).
Special Instructions
Not provided.
Limitations
This test's performance characteristics have been determined by ARUP Laboratories but it has not been FDA cleared or approved. Clotted or hemolyzed specimens are unacceptable, as are serum and EDTA plasma.
New York Approved
Methodology
Other
Biomarkers
Factor VIII
Analyte
LOINC Codes
- 49865-9 - Fact VIII Act/Nor PPP Chro
Result Turnaround Time
1-4 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
1 mL
Minimum Volume
0.8 mL
Container
ARUP standard transport tube
Collection Instructions
Transfer 1 mL platelet-poor plasma to an ARUP standard transport tube after collection in a light blue (sodium citrate) tube.
Storage Instructions
CRITICAL FROZEN
Causes for Rejection
Serum or EDTA plasma; clotted or hemolyzed specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 4 hours |
| Refrigerated | Unacceptable |
| Frozen | 3 months |
Other tests from different labs that may be relevant