Collagen Type VII Antibody, IgG by ELISA
Also known as: COLLAG 7
Use
The test is used to monitor disease in patients diagnosed with epidermolysis bullosa acquisita (EBA) or bullous lupus erythematosus who have increased IgG type VII collagen antibody levels. It is not intended as an initial diagnostic tool but rather for monitoring disease progression or changes. Initial diagnosis and discrimination among various immunobullous diseases are better served by using broader antibody panels such as the Immunobullous Disease Antibody Panel or Basement Membrane Zone Antibody Panel.
Special Instructions
Not provided.
Limitations
The test is not suitable for initial diagnosis of immunobullous diseases as it may not detect antibodies to basement membrane zone antigens other than type VII collagen epitopes displayed in this ELISA. It also does not rule out other disorders with similar symptoms, such as anti-laminin-332 pemphigoid or anti-p200 pemphigoid, especially if associated with other conditions.
New York Approved
Methodology
Immunoassay (ELISA)
Biomarkers
Collagen Type VII
Protein
Result Turnaround Time
3-9 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
2 mL
Minimum Volume
0.5 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Transfer 2 mL serum to an ARUP Standard Transport Tube.
Storage Instructions
Store refrigerated unless shipping promptly (within 2 hours). Transport at ambient temperature to arrive within 7 days. If 7-14 days until received in laboratory, store and ship refrigerated. If greater than 14 days, serum specimens must be stored and shipped frozen.
Causes for Rejection
Hemolyzed or lipemic specimens. Plasma.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 1 week |
| Refrigerated | 2 weeks |
| Frozen | Indefinitely |
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