Copper, Random Urine
Also known as: U COP RAND
Use
This test is useful in assessing copper overload, particularly in individuals with conditions like Wilson disease, cholestatic liver disease, and proteinuria, where elevated urine copper levels can be indicative. While random urine samples may contain diagnostic information, a 24-hour urine collection is recommended for a consistent indicator of urine copper levels.
Special Instructions
Patients should discontinue nutritional supplements, vitamins, minerals, and nonessential over-the-counter medications if possible. Avoid sample collection from patients who have recently received iodinated or gadolinium-based contrast media for at least 72 hours post-exposure, or for at least 14 days from patients with impaired kidney function.
Limitations
High concentrations of iodine or gadolinium can interfere with elemental testing, leading to potentially inaccurate results. Additionally, elevated results may be due to contamination from collection containers not certified as trace element-free. If contamination is suspected, confirmation with a second specimen in a certified trace element-free container is recommended.
New York Approved
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 30920-3
- 35674-1
- 13829-7
Result Turnaround Time
1-5 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
8 mL
Minimum Volume
1 mL
Container
ARUP Trace Element-Free Transport Tubes
Collection Instructions
Transfer an aliquot from a well-mixed random urine collection into the specified transport tubes.
Patient Preparation
Discontinue use of nutritional supplements, vitamins, minerals, and nonessential medications. Avoid collection within 72 hours of administration of contrast media.
Storage Instructions
Refrigerated transport recommended. Room temperature or frozen conditions are also acceptable.
Causes for Rejection
Samples collected within 72 hours of contrast media administration, acid-preserved urine, use of non-specified containers, or contamination with blood or fecal material.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 1 week |
| Refrigerated | 2 weeks |
| Frozen | 1 year |