Corynebacterium diphtheriae Culture
Also known as: MC DIPH
Use
The Corynebacterium diphtheriae Culture test is used to identify the presence of C. diphtheriae in clinical specimens, which is crucial for diagnosing diphtheria. This infection can result in severe respiratory illness and complications, making accurate identification essential for timely treatment and public health management. The test involves culturing the bacteria from samples collected, typically from nasopharynx, throat, or wound swabs.
Special Instructions
Clinical specimens should be collected from the nasopharynx, throat, or wound. The swabs must be submitted in bacterial transport media. Separate orders are required for each collected swab. Note that specimens in UTM or other viral transport media are not acceptable for this test.
Limitations
This test is not suitable for specimens stored under refrigerated or frozen conditions, as these are considered unacceptable. Culture results are negative if no Corynebacterium diphtheriae is isolated. Positive identification may require confirmatory toxin testing by the CDC, as part of the workflow after organism isolation.
New York Approved
Methodology
Culture-based
Biomarkers
LOINC Codes
- 16676-9
Result Turnaround Time
1-4 days
Related Documents
For more information, please review the documents below
Specimen
Nasopharyngeal Swab
Volume
Not provided
Minimum Volume
Not provided
Container
bacterial transport media
Collection Instructions
Swab nasopharynx and throat at the site of membrane or inflammation to increase recovery. Swab base of cleansed wound, if present.
Storage Instructions
Room temperature.
Causes for Rejection
Specimens in UTM or other viral transport media.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | Unacceptable |
| Frozen | Unacceptable |