Coxsackie B Virus Antibodies
Also known as: COX B
Use
The Coxsackie B Virus Antibodies test detects neutralizing antibodies to Coxsackie B virus. It is used to diagnose past or current infections. A single positive antibody titer of greater than or equal to 1:80 may indicate a past or current infection. Seroconversion or an increase in titers between acute and convalescent sera of at least fourfold is considered strong evidence of current or recent infection. PCR testing is preferred for diagnosing acute infections.
Special Instructions
Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of acute specimens. Mark specimens plainly as 'acute' or 'convalescent'.
Limitations
The test should not be used as the sole basis for diagnosis. Conditions like contamination, hemolysis, or severe lipemia can lead to specimen rejection. The test uses semi-quantitative serum neutralization methodology, and results are subjected to biological variability in antibody levels. The storage and handling of specimens, like avoiding repeated freeze/thaw cycles, are critical for accurate results.
New York Approved
Methodology
Other
Biomarkers
LOINC Codes
- 5103-7
- 5105-2
- 5107-8
- 5109-4
- 5111-0
- 5113-6
- 5103-7
- 5105-2
- 5107-8
- 5109-4
- 5111-0
- 5113-6
Result Turnaround Time
6-12 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.3 mL
Container
Serum Separator Tube (SST) or Plain Red
Collection Instructions
Separate from cells ASAP or within 2 hours of collection. Transfer to an ARUP Standard Transport Tube.
Storage Instructions
Refrigerated.
Causes for Rejection
CSF or plasma. Contaminated, hemolyzed, or severely lipemic specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 year |