Cytomegalovirus by Qualitative PCR
Also known as: CMVPCR
Use
The qualitative detection of cytomegalovirus (CMV) DNA by polymerase chain reaction (PCR) is used to diagnose CMV infection. This test is beneficial for identifying CMV presence in patients where quantification is not required. It is particularly useful for screening in bone marrow transplants, detecting congenital infections, and diagnosing CMV-related complications in immunocompromised individuals. This test does not provide viral load quantification; if quantification is needed, refer to other specific tests.
Special Instructions
Not provided.
Limitations
This test detects the presence of CMV DNA but does not quantify the viral load, which limits its use in monitoring disease progression or response to treatment where viral load is relevant. It might not detect the virus in all cases, particularly when viral DNA is present below the detection level or when PCR inhibitors are present in the sample. Therefore, a negative result does not definitively exclude the presence of CMV. Heparinized specimens and tissues in optimal cutting temperature compound are not acceptable as they can interfere with the PCR process.
New York Approved
Methodology
PCR-based (PCR)
Biomarkers
Cytomegalovirus
Microorganism
LOINC Codes
- 31208-2 - Specimen source
- 5000-5 - CMV DNA Spec Ql NAA+probe
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Bone Marrow
Volume
1 mL
Minimum Volume
0.5 mL
Container
sterile container
Storage Instructions
Frozen
Causes for Rejection
Heparinized specimens
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 1 week |
| Refrigerated | 1 week |
| Frozen | 1 week |
Other tests from different labs that may be relevant