D-Dimer
Also known as: D-DI
Use
The D-Dimer test aids in diagnosing and monitoring disseminated intravascular coagulation (DIC). It measures the amount of cross-linked fibrin degradation products present in the blood, which are indicative of the body's process of breaking down blood clots. This test is critical in the context of various clotting disorders and helps to provide a clearer picture of a patient's clotting status, although it should not be used as a standalone test to rule out venous thromboembolism.
Special Instructions
Specimens for this test are critically frozen and should be transported separately when multiple tests are ordered from the same patient, to avoid degradation of the specimen.
Limitations
The presence of rheumatoid factor may cause false-positive results with the D-Dimer test. D-Dimer results must be interpreted carefully, and it should not be relied upon solely to rule out venous thromboembolism. Maximal D-Dimer values of less than 10 µg/mL FEU are rarely indicative of DIC and should be considered in the broader clinical context.
FDA ApprovedNew York Approved
Methodology
Immunoassay (Immunoturbidimetry)
Biomarkers
LOINC Codes
- 48065-7
Result Turnaround Time
1 day
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
2 mL
Minimum Volume
0.5 mL
Container
ARUP standard transport tube
Patient Preparation
Collect into light blue (sodium citrate) tube. Separate and freeze plasma immediately after collection.
Storage Instructions
CRITICAL FROZEN. Separate and freeze plasma immediately.
Causes for Rejection
Serum, EDTA plasma, clotted, or hemolyzed specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 8 hours |
| Refrigerated | Unacceptable |
| Frozen | 1 month |