Drug Profile, Expanded Targeted Panel by LC-MS/MS, Serum/Plasma
Also known as: COMPDRUGSP
Use
This test is used to detect drug exposure from a targeted list of prescription, over-the-counter medications, and illicit drugs. It is important for medical purposes although it is not valid for forensic use. The absence of expected drugs or metabolites may indicate noncompliance, inappropriate timing of specimen collection relative to drug administration, poor drug absorption, or limitations of testing. This assay detects 127 drugs and drug metabolites by LC-MS/MS, and results are used to guide clinical interpretations regarding drug exposure.
Special Instructions
Not provided.
Limitations
This qualitative drug panel is not recommended for determining medication compliance or assessing undisclosed drug/substance use in the context of pain management, substance use disorder treatment, or other pharmacotherapies involving controlled substances. It has limitations due to potential noncompliance, inappropriate timing of specimen collection, poor drug absorption, or inherent testing limitations. The concentration of drugs/metabolites varies within classes and must meet the cutoff for a positive report. Interpretative inquiries should be directed to the laboratory.
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 80197-7 - H1 recep antag SerPl Ql Scn
- 61128-5 - Cotinine SerPl Ql
- 3538-6 - D-methorphan SerPl Ql
- 3297-9 - APAP SerPl Ql
- 33040-7 - Hypnotics SerPl Ql Scn
Result Turnaround Time
1-9 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
4 mL
Minimum Volume
2 mL
Container
ARUP standard transport tube
Collection Instructions
Separate serum from cells ASAP or within 2 hours of collection.
Storage Instructions
Refrigerated.
Causes for Rejection
Gel separator tubes or light blue (sodium citrate), specimens exposed to repeated freeze/thaw cycles, postmortem specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 24 hours |
| Refrigerated | 2 weeks |
| Frozen | 2 months |
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