Ehrlichia chaffeensis Antibody, IgG by IFA
Also known as: E CH G
Use
This test is used to detect antibodies to Ehrlichia chaffeensis, most useful during the convalescent phase of the disease. It aids in diagnosing human monocytic ehrlichiosis (HME), a tick-borne disease caused by rickettsial-like agents. Detecting a significant change in titer between acute and convalescent sera, where both tests are performed in the same laboratory, is considered strong evidence of recent infection.
Special Instructions
Parallel testing is preferred, and convalescent specimens should be received within 30 days of acute specimens. Mark specimens clearly as acute or convalescent to facilitate proper processing and comparison.
Limitations
The test detects IgG antibodies, which may indicate past exposure rather than active infection. PCR testing is preferred for diagnosing active infections. The test should not be used as a standalone diagnostic tool without considering the clinical context and other diagnostic information.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
LOINC Codes
- 47405-6
Result Turnaround Time
1-5 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.4 mL
Container
Serum Separator Tube
Collection Instructions
Separate serum from cells ASAP or within 2 hours of collection. Transfer serum to an ARUP standard transport tube.
Storage Instructions
Refrigerate specimens after collection.
Causes for Rejection
Contaminated, hemolyzed, or severely lipemic specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 year (avoid repeated freeze/thaw cycles) |