Eosinophil Cationic Protein (ECP)
Also known as: EC PROT
Use
The Eosinophil Cationic Protein (ECP) test is designed to monitor inflammation caused by asthma and to optimize corticosteroid treatment in asthmatic patients. Elevated levels of ECP are associated with eosinophilic inflammation and can be indicative of asthma activity. The test aids in evaluating the effectiveness of therapeutic interventions and in guiding dosage adjustments for improved patient outcomes.
Special Instructions
Ensure proper handling of the serum separator tube to avoid hemolysis, lipemia, or icterus, which are unacceptable conditions for testing. Follow specified specimen preparation instructions carefully.
Limitations
This test was developed and its performance characteristics were determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. Caution is advised in the interpretation of results, as this is a Laboratory Developed Test intended for clinical purposes. Results should be considered in conjunction with clinical evaluation and not as a standalone diagnostic tool.
New York Approved
Methodology
Immunoassay (Quantitative Fluorescent Enzyme Immunoassay)
Biomarkers
LOINC Codes
- 25638-8
Result Turnaround Time
1-8 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.25 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Collect blood by venipuncture using a Serum separator tube (SST). Gently invert the tube several times. Do not shake or vortex the tube. Allow ECP to be released by clotting for 60-120 minutes at room temperature (20-24° C). Centrifuge at 1000-1300 x g for 10 minutes at room temperature.
Storage Instructions
Frozen, also acceptable; Refrigerated
Causes for Rejection
Plasma, hemolyzed, lipemic and icteric serum cannot be used.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 5 Days |
| Frozen | 30 Days |