ERG by Immunohistochemistry
Also known as: ERG IHC
Use
The ERG by Immunohistochemistry test is a laboratory-developed stain and–return technical service intended for clinical purposes, performed in a CLIA-certified laboratory. It was developed and validated by ARUP Laboratories; however, it has not been cleared or approved by the U.S. Food and Drug Administration. It is used to detect ERG protein expression in tissue specimens via immunohistochemistry, providing interpretive data for diagnostic evaluation. New York State Department of Health approval status is positive.
Special Instructions
Not provided.
Limitations
Specimens with non-representative tissue type or depleted specimens are unacceptable. Slides must not be oven baked if precut; specimens must be formalin-fixed and paraffin-embedded into cellblock format. Frozen specimens are unacceptable. The test is not FDA-cleared or approved, limiting generalizability beyond CLIA laboratory validation.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
ERG
Protein
LOINC Codes
- 94736-6 - Tissue block ID Spec
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tumor Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
Tissue block or 5 unstained slides (3–5 micron, positively charged)
Collection Instructions
Formalin fix (10 percent neutral buffered formalin) and paraffin embed specimen into cellblock; protect from excessive heat; transport tissue block or 5 unstained sections; if sending precut slides, do not oven bake; ARUP transport kit recommended.
Storage Instructions
Room temperature or refrigerated; ship cooled in summer months.
Causes for Rejection
Non-representative tissue type; depleted specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinitely |
| Refrigerated | Indefinitely |
| Frozen | Unacceptable |
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