Factor IX, Activity
Also known as: F9
Use
The Factor IX, Activity test is used for diagnosing factor IX deficiency, also known as hemophilia B. It is a critical component in the coagulation cascade and is essential for normal blood clotting. This test is particularly important for monitoring patients undergoing treatment for hemophilia B with factor IX replacement therapy, ensuring that they maintain adequate levels for effective hemostasis.
Special Instructions
Specimens must be transported critically frozen to ensure test accuracy. Separate specimens are required if multiple tests are ordered from the patient. EDTA plasma or serum, as well as clotted or hemolyzed specimens, are unacceptable for testing.
Limitations
This test is designed for measuring the activity of factor IX specifically. It may not detect abnormalities not related to factor IX activity, such as other clotting factor deficiencies or platelet disorders. Proper specimen handling is critical; any deviation can lead to inaccurate results. Results may also be impacted by certain anticoagulant medications, which should be disclosed prior to testing.
New York Approved
Methodology
Other
Biomarkers
LOINC Codes
- 3187-2
- 3187-2
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
2 mL
Minimum Volume
1 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Collect in a Lt. blue (sodium citrate) tube. Transfer 2 mL of platelet-poor plasma to the transport tube.
Storage Instructions
CRITICAL FROZEN. Specimens must remain frozen during transport.
Causes for Rejection
Serum, EDTA plasma, clotted or hemolyzed specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 4 hours |
| Refrigerated | Unacceptable |
| Frozen | 2 weeks |