Fentanyl and Metabolite, Serum or Plasma, Quantitative
Also known as: CDCO FNSP
Use
The test is used to monitor patient adherence to fentanyl therapy. It measures the concentrations of fentanyl and its metabolite, norfentanyl, in serum or plasma to ensure that the patient is taking the medication as prescribed. The test aids in verifying compliance, optimizing therapeutic outcomes, and preventing unintentional overdose or drug accumulation.
Special Instructions
For medical purposes only; not valid for forensic use. Specimens should be collected in specific tubes (plain red, lavender, green, gray, or pink) and separated from cells as soon as possible or within two hours. The concentration value must be greater than or equal to the cutoff of 0.1 ng/mL to be reported as positive.
Limitations
The absence of expected drug(s) and/or metabolite(s) may indicate non-compliance, inappropriate timing of specimen collection relative to drug administration, poor drug absorption, or limitations of testing. The methodology might not detect concentrations below the cutoff. It is important to interpret the results in conjunction with clinical findings and other laboratory data.
New York Approved
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 11074-2
- 3636-8
- 3636-8
- 11074-2
Result Turnaround Time
1-8 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
4 mL
Minimum Volume
2 mL
Container
ARUP standard transport tube
Collection Instructions
Separate from cells ASAP or within 2 hours of collection.
Storage Instructions
Refrigerated.
Causes for Rejection
Whole blood. Serum separator tubes, light blue (sodium citrate), or plasma separator tubes. Specimens exposed to repeated freeze/thaw cycles.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 1 week |
| Refrigerated | 2 weeks |
| Frozen | 3 years |