FGFR1 Gene Amplification by FISH
Also known as: FGFR1_FISH
Use
The FGFR1 Gene Amplification by FISH test is used to screen for FGFR1 gene amplification, which aids in prognostication and therapeutic decision-making for neoplasms where amplification has been demonstrated. It provides insight into the genetic alterations of tumors and assists in guiding targeted therapy decisions.
Special Instructions
Include a surgical pathology report. If multiple specimens (blocks or slides) are sent, they must be accompanied by an order comment indicating specimen selection guidance or individual orders for each sample. A Pathologist Block Selection Fee may be applied for selection services.
Limitations
This test is developed and its performance characteristics determined by ARUP Laboratories. It is a laboratory-developed test (LDT) and has not been cleared or approved by the US FDA. It is conducted in a CLIA-certified laboratory for clinical purposes. Interpretation should be in the context of all pertinent clinical and laboratory data.
New York Approved
Methodology
Chromosomal / Cytogenetics (FISH)
Biomarkers
LOINC Codes
- 81304-8
- 78916-4
- 78917-2
- 80398-1
Result Turnaround Time
3-7 days
Related Documents
For more information, please review the documents below
Specimen
Tumor Tissue (FFPE)
Volume
Not provided
Minimum Volume
4 slides
Container
Positively charged glass slides or paraffin block
Collection Instructions
Formalin fix (10 percent neutral buffered formalin) and paraffin embed tumor tissue.
Storage Instructions
Protect paraffin block and/or slides from excessive heat.
Causes for Rejection
Paraffin block with no tumor tissue remaining. Specimens fixed in any fixative other than 10 percent neutral buffered formalin. Decalcified specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinitely |
| Refrigerated | Indefinitely |
| Frozen | Unacceptable |