FGFR1 Gene Amplification by FISH
Also known as: FGFR1_FISH
Use
The FGFR1 Gene Amplification by FISH test is used to screen for FGFR1 gene amplification, which aids in prognostication and therapeutic decision-making for neoplasms where amplification has been demonstrated. It provides insight into the genetic alterations of tumors and assists in guiding targeted therapy decisions.
Special Instructions
Not provided.
Limitations
This test is developed and its performance characteristics determined by ARUP Laboratories. It is a laboratory-developed test (LDT) and has not been cleared or approved by the US FDA. It is conducted in a CLIA-certified laboratory for clinical purposes. Interpretation should be in the context of all pertinent clinical and laboratory data.
New York Approved
Methodology
Chromosomal / Cytogenetics (FISH)
Biomarkers
No genes
Gene
LOINC Codes
- 81304-8 - Struct var analysis method
- 78916-4 - FGFR1 gene rearr Bld/T FISH-Imp
- 78917-2 - Cells.FGFR1 rearr/Cells cnt Bld/T FISH
- 80398-1 - Unique ID Current sample
Result Turnaround Time
3-7 days
Related Documents
For more information, please review the documents below
Specimen
Tumor Tissue (FFPE)
Volume
Not provided
Minimum Volume
4 slides
Container
Positively charged glass slides or paraffin block
Collection Instructions
Formalin fix (10 percent neutral buffered formalin) and paraffin embed tumor tissue.
Storage Instructions
Protect paraffin block and/or slides from excessive heat.
Causes for Rejection
Paraffin block with no tumor tissue remaining. Specimens fixed in any fixative other than 10 percent neutral buffered formalin. Decalcified specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Indefinitely |
| Refrigerated | Indefinitely |
| Frozen | Unacceptable |
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