Flecainide
Also known as: FLEC
Use
The Flecainide test is used for optimizing drug therapy and monitoring patient adherence. It is primarily utilized in therapeutic drug monitoring to ensure that patients maintain therapeutic levels of Flecainide while avoiding toxicity. This test helps in preventing cardiac abnormalities, hypotension, and seizures that may be associated with toxic concentrations of the drug.
Special Instructions
Timing of specimen collection should be pre-dose (trough) and at steady state concentration. Gel separator tubes or gels of any kind are unacceptable as they cause immediate drug loss, resulting in no testing being performed.
Limitations
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration, but it is intended for clinical purposes and performed in a CLIA certified laboratory. Interpretive data suggests that toxic concentrations can cause cardiac abnormalities, hypotension, or seizures.
New York Approved
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 3638-4
Result Turnaround Time
1-8 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
2 mL
Minimum Volume
0.5 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Separate serum or plasma from cells within 6 hours of collection.
Patient Preparation
Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration.
Storage Instructions
Refrigerated transport is required.
Causes for Rejection
Gel separator tubes or gels of any kind; drug loss is immediate and no testing will be performed.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 6 weeks |
| Refrigerated | 6 weeks |
| Frozen | 6 weeks |