Glomerular Basement Membrane Antibody, IgG (IFA)
Also known as: GBM-G IFA
Use
The Glomerular Basement Membrane Antibody, IgG (IFA) test is used to detect antibodies against the glomerular basement membrane (GBM) antigen, which can be indicative of Goodpasture syndrome. The presence of these antibodies detected by either indirect fluorescent antibody (IFA) or multiplex bead assay can support the diagnosis of the disease. These antibodies are associated with autoimmune kidney diseases and their detection can be useful for monitoring treatment response when combined with other assays.
Special Instructions
Not provided.
Limitations
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration, and is performed in a CLIA certified laboratory intended for clinical purposes. The combined use of multiple assays increases diagnostic sensitivity, and a positive result should be corroborated with a renal biopsy. Assay performance and diagnostic accuracy may vary, and results should be interpreted in context with clinical findings.
New York Approved
Methodology
Immunoassay (Indirect Fluorescent Antibody (IFA))
Biomarkers
GBM Antibody, IgG
Analyte
LOINC Codes
- 29994-1 - BM IgG Ser Ql IF
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
Serum separator tube.
Collection Instructions
Separate serum from cells ASAP or within 2 hours of collection.
Storage Instructions
Refrigerated.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 year |
Other tests from different labs that may be relevant