Growth Hormone, Timed - Other
Also known as: GH OTHER
Use
For pediatric patients, very low peak growth hormone (GH) concentrations on stimulation testing are consistent with severe GH deficiency (GHD). Thresholds distinguishing normal from partial GHD have not been well established. Inadequate response to two different provocative tests is required for diagnosis of GHD. In adults, expected peak GH concentrations depend on the stimulation test performed, as described in Endocrine Society guidelines for the evaluation and treatment of adults with GHD. For suppression testing, healthy subjects have GH concentrations of less than 1 ng/mL within 2 hours of ingestion of a glucose dose. Patients with acromegaly fail to show normal suppression.
Special Instructions
Not provided.
Limitations
Thresholds for distinguishing normal from partial GH deficiency have not been well established. Inadequate response to two different provocative tests is required for diagnosis of GH deficiency. Peak GH concentrations depend on the stimulation test performed and are described in Endocrine Society guidelines.
New York Approved
Methodology
Immunoassay (CLIA)
Biomarkers
Growth Hormone
Analyte
LOINC Codes
- 50220-3 - Collect interval from BL Time Spec
- 2963-7 - GH SerPl-mCnc
Result Turnaround Time
1-2 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
1 mL
Minimum Volume
0.4 mL
Container
Plasma separator tube or serum separator tube
Storage Instructions
Frozen
Causes for Rejection
Tissue or urine. Grossly hemolyzed or lipemic specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 24 hours |
| Refrigerated | 1 week |
| Frozen | 2 months |
Other tests from different labs that may be relevant