Herpesvirus 6 Antibody, IgG
Also known as: HHV6 G
Use
Human Herpesvirus 6 (HHV-6) infects T-lymphocytes and is associated with conditions such as exanthema subitum. The detection of HHV-6 antibodies indicates prior exposure, but due to the high prevalence of these antibodies, the presence of a single titer has limited clinical value. Serologic evidence of an acute infection or reactivation is demonstrated by a significant rise or seroconversion of IgG and IgM titers. This test, when used in conjunction with the Herpesvirus 6 Antibody, IgM by IFA, Serum, assists in diagnosing HHV-6 disease in immunocompromised adults.
Special Instructions
The test is not performed at ARUP Laboratories, so separate specimens must be submitted when multiple tests are ordered. Recommended to consider Human Herpesvirus 6 (HHV-6A and HHV-6B) by Quantitative PCR for suspected meningitis cases.
Limitations
Due to the high prevalence of HHV-6 antibodies, correlations of single titers with specific diseases are of limited clinical value. This test has not been cleared or approved by the FDA but has been validated under CLIA regulations for clinical use.
New York Approved
Methodology
Immunoassay (Indirect Fluorescent Antibody)
Biomarkers
LOINC Codes
- 25416-9
Result Turnaround Time
5-9 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL
Minimum Volume
0.1 mL
Container
Plain red or serum separator tube (SST)
Collection Instructions
Transfer serum to an ARUP standard transport tube.
Storage Instructions
Refrigerated storage is preferred, but serum is also acceptable at room temperature or frozen.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 1 week |
| Refrigerated | 2 weeks |
| Frozen | 1 month |