Histoplasma and Blastomyces by PCR
Also known as: HIBL PCR
Use
This test serves as an adjunct in the diagnosis of histoplasmosis and blastomycosis. It is not a substitute for culture and/or antigen testing. Histoplasmosis and blastomycosis are fungal infections that can cause serious disease, especially in immunocompromised individuals. Detecting the presence of Histoplasma capsulatum or Blastomyces species through PCR can aid in timely diagnosis and management of these infections.
Special Instructions
Not provided.
Limitations
A negative result does not rule out the presence of PCR inhibitors in the patient specimen or the presence of test-specific nucleic acid at concentrations below the level of detection. The test does not differentiate between Blastomyces dermatitidis and Blastomyces gilchristii. It was developed and its performance characteristics determined by ARUP Laboratories. The test has not been cleared or approved by the U.S. FDA but is performed in a CLIA-certified laboratory for clinical purposes.
New York Approved
Methodology
PCR-based (PCR)
Biomarkers
Blastomyces dermatitidis
MicroorganismBlastomyces gilchristii
MicroorganismHistoplasma capsulatum
Microorganism
LOINC Codes
- 31208-2 - Specimen source
- 95917-1 - H capsul DNA Lower resp Ql NAA+probe
- 95916-3 - Blastomyces DNA Lower resp Ql NAA+probe
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Bronchoalveolar Lavage
Volume
2 mL
Minimum Volume
1.2 mL
Container
Sterile container
Collection Instructions
Transfer bronchoalveolar lavage (BAL) to a sterile container.
Storage Instructions
Freeze immediately after transfer to a sterile container.
Causes for Rejection
Formalin-fixed paraffin embedded tissue
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Unacceptable |
| Refrigerated | 14 days |
| Frozen | 14 days |
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