Immunoglobulin A Subclasses (1 and 2)
Also known as: IGA SUB
Use
The Immunoglobulin A Subclasses (1 and 2) test aids in the diagnosis and monitoring of immune disorders caused by IgA deficiency. It measures the levels of total Immunoglobulin A (IgA) as well as its subclasses 1 and 2, providing comprehensive insights into a patient's immune system status. This test is useful in assessing patients with recurrent infections, autoimmune diseases, and other conditions related to IgA deficiency.
Special Instructions
For accurate results, ensure proper specimen collection and handling as specified. The test requires serum collected in a serum separator tube, transferred to an ARUP Standard Transport Tube.
Limitations
The test results may be affected by factors such as hemolysis, lipemia, or the presence of rheumatoid factor, circulating immune complexes, or paraproteinemia. It's important to consider these aspects while interpreting the results, as they may cause discrepancies between the total IgA concentration and the sum of the subclass concentrations.
New York Approved
Methodology
Immunoassay (Immunoturbidimetry)
Biomarkers
LOINC Codes
- 2458-8
- 6886-6
- 6939-3
Result Turnaround Time
1-5 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
2 mL
Minimum Volume
0.7 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Collect in a serum separator tube and transfer to ARUP Standard Transport Tube.
Storage Instructions
Refrigerate the specimen after collection.
Causes for Rejection
Grossly hemolyzed or lipemic specimens
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Unacceptable |
| Refrigerated | 14 days |
| Frozen | 6 months |