Immunoglobulin G Subclasses (1, 2, 3, 4)
Also known as: IGG SUB
Use
This test aids in the evaluation of patients suspected of having humoral immunodeficiency or combined immunodeficiency, either humoral or cellular. It's used as a second-order test to help diagnose these conditions by measuring the levels of the different subclasses of Immunoglobulin G in the serum. The results can provide insights into the patient's immune function and the potential need for immune system-related interventions.
Special Instructions
Serum needs to be separated from cells quickly, ideally within 2 hours of collection, to ensure the accuracy of test results. Transport the serum sample in ARUP Standard Transport Tube under refrigerated conditions. Ensure the sample is not grossly hemolyzed or lipemic as this can affect test results.
Limitations
This test may have limitations in distinguishing between subclasses in the presence of certain co-existing conditions or treatments. The results should be interpreted in the context of the entire clinical picture and possibly in conjunction with other immunological assessments. Grossly hemolyzed or lipemic specimens are unacceptable and could lead to inaccurate results.
FDA ApprovedNew York Approved
Methodology
Immunoassay (Quantitative Immunoturbidimetry)
Biomarkers
LOINC Codes
- 2466-1
- 2467-9
- 2468-7
- 2469-5
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
2 mL
Minimum Volume
1 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Separate serum from cells ASAP or within 2 hours of collection. Transfer to an ARUP Standard Transport Tube.
Storage Instructions
Refrigerate the specimen for transportation.
Causes for Rejection
Grossly hemolyzed or lipemic specimens
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Unacceptable |
| Refrigerated | 14 days |
| Frozen | 6 months |