Insulin, 60 Minutes
Also known as: INSULIN 60
Use
The Insulin, 60 Minutes test measures insulin levels in serum to evaluate the patient's insulin response following glucose intake. This test is valuable in assessing insulin secretion and could help diagnose or monitor conditions related to insulin resistance and diabetes. It provides information about how a patient's insulin levels respond within 60 minutes of a glucose challenge, typically performed as part of an oral glucose tolerance test.
Special Instructions
Ensure the specimen is collected in a serum separator tube and allowed to clot completely at room temperature. Separate serum from cells within 2 hours and transfer to an ARUP Standard Transport Tube for transport under frozen conditions. This test is approved for use in New York state.
Limitations
The test may exhibit cross-reactivity with various insulin analogs. It reacts nearly equimolarly with insulin aspart, insulin glargine, and insulin lispro, whereas insulin detemir shows about 50% cross-reactivity. The test has negligible reactivity with insulin glulisine (<3%). Potential interference could arise from improper specimen handling such as hemolysis, or from unacceptable specimen types such as heparinized plasma and I.V./vitreous fluids.
New York Approved
Methodology
Immunoassay (CLIA)
Biomarkers
LOINC Codes
- 27379-7
Result Turnaround Time
1 day
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.4 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Collect in a serum separator tube. Allow specimen to clot completely at room temperature. Separate serum from cells ASAP or within 2 hours and transfer to transport tube.
Storage Instructions
Frozen
Causes for Rejection
Heparinized plasma, I.V. fluid, vitreous fluid, gray (sodium fluoride/potassium oxalate), hemolyzed specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 8 hours |
| Refrigerated | 1 week |
| Frozen | 1 month |