Ketamine and Metabolite Quantitative, Serum or Plasma
Also known as: KETAMINE S
Use
This test is used to monitor patient adherence and exposure to ketamine. It measures the quantitative levels of ketamine and its primary metabolite, norketamine, in serum or plasma. Detection of these substances can help in assessing proper therapeutic dosing or potential misuse. It is commonly employed in emergency toxicology and therapeutic drug monitoring contexts to ensure the safe and effective use of ketamine, particularly during anesthesia or in clinical settings requiring its use.
Special Instructions
The test is performed by NMS Labs and is not conducted at ARUP Labs. Separate specimens must be submitted when multiple tests are ordered. Samples must be separated from cells as soon as possible or within two hours of collection before transferring to an ARUP standard transport tube.
Limitations
This test has not been cleared or approved by the U.S. Food and Drug Administration and was developed with its performance characteristics determined by NMS Labs. There may be limitations in terms of detection limits and potential interference from other similar compounds. Moreover, digital data review may occur remotely by qualified NMS staff, adhering to CLIA regulations, which highlights the robust procedures in place but also alludes to the limitations in manual result verification.
New York Approved
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 3701-0
- 21421-3
Result Turnaround Time
5-8 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.3 mL
Container
ARUP standard transport tube
Collection Instructions
Separate from cells ASAP or within 2 hours of collection.
Storage Instructions
Refrigerated is preferred, though room temperature or frozen are also acceptable.
Causes for Rejection
Separator tubes
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 2 weeks |
| Refrigerated | 2 weeks |
| Frozen | 9 months |