Lead, Urine
Also known as: LEAD U
Use
This test is useful in the assessment of chronic lead exposure and monitoring chelation therapy. It helps in evaluating potential lead poisoning by quantifying the amount of lead excreted in urine over a specified time period. The test can be essential for individuals with occupational exposure to lead, or in those undergoing treatment to remove excess lead from the body.
Special Instructions
The test requires careful specimen collection to avoid contamination and ensure accurate results. Patients should discontinue certain supplements and medications upon physician advice to prevent interference. Collection should avoid periods soon after contrast media exposure.
Limitations
Urine samples collected soon after the administration of iodinated or gadolinium-based contrast media are not acceptable due to potential interference. The test may return falsely elevated results if collection containers are not certified to be trace element-free. Elevated results should be confirmed with a second specimen if contamination is suspected. Other factors such as improper collection method and contamination from skin or collection devices can affect results.
New York Approved
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 35674-1
- 2162-6
- 5677-0
- 30931-0
- 13466-8
- 19153-6
- 30211-7
Result Turnaround Time
1-5 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
8 mL
Minimum Volume
1 mL
Container
ARUP Trace Element-Free Transport Tubes
Collection Instructions
24-hour or random urine collection in a plastic container. Record total volume and collection time on transport tube and test request form. Avoid collection within 72 hours after iodinated or gadolinium media exposure.
Patient Preparation
Discontinue non-essential supplements, vitamins, minerals upon physician advice. Avoid collection post-iodinated/gadolinium media exposure for 72 hours. For impaired kidney function, avoid collection for 14 days post-exposure.
Storage Instructions
Store refrigerated. Also acceptable at room temperature or frozen.
Causes for Rejection
Urine within 72 hours post-contrast media, acid preserved urine, contaminated with blood or fecal material, non-trace element-free transport tubes.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 1 week |
| Refrigerated | 2 weeks |
| Frozen | 1 year |