Lymphocyte Subset Panel 1 - CD4 Absolute Count Only

Also known as: ABS4

Clinical Use

Use

The Lymphocyte Subset Panel 1 - CD4 Absolute Count Only test aids in the clinical management of HIV-positive individuals. CD4 cells, also known as Helper T-cells, are a type of white blood cell that express both CD3 and CD4 antigens. These cells are critical in the body's immune response, particularly in the context of HIV infection. Monitoring the absolute count of CD4 T-cells is essential in categorizing HIV-related clinical conditions as per the CDC's classification system. The measurement of CD4 T-cell levels assists in establishing decision points for initiating prophylaxis against P. jirovecii, antiviral therapy, and monitoring the efficacy of HIV treatment. The Public Health Service recommends that CD4 T-cell levels be monitored every 3 to 6 months in all HIV-infected persons.

Special Instructions

Not provided.

Limitations

The test is not approved for New York State clients and requires whole blood specimens to be analyzed within the specified ambient stability times, as refrigerated or frozen storage conditions are unacceptable. Clotted or hemolyzed specimens are also deemed unacceptable. The test performance was determined by ARUP Laboratories, and it has not obtained FDA clearance or approval. The test aids in assessing CD4 levels below critical thresholds for prophylactic interventions, providing crucial data for HIV treatment management, although it does not assess additional CBC data.

Test Details